English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The use of milk to deliver Eubacterium coprostanoligenes, a cholesterol-reducing bacteria, to decrease plasma cholesterol concentration was investigated in hypercholesterolemic rabbits. Eighteen adult male New Zealand White rabbits were randomly divided into three groups and fed a no cholesterol diet (control) , control diet supplemented with 0.1% cholesterol and boiled E. coprostanoligenes in 2% minimal fat homogenized milk diet or control diet supplemented with 0.1% cholesterol and E. coprostanoligenes in 2% fat homogenized milk for 21 days. No clinical signs or symptoms of bacterial intoxication were observed in any rabbit. There were no significant differences in rabbit mean body weight during the different feeding periods. There were no significant differences between total plasma cholesterol concentration in rabbits fed the 0.1% cholesterol + boiled E. coprostanoligenes in 2% fat 58 homogenized milk diet, and a 0.1% cholesterol + E. coprostanoligenes in 2% fat homogenized milk. However, changes in total plasma cholesterol concentration from day 0-77 in rabbits fed the 0.1% cholesterol + E. coprostanoligenes in 2% fat homogenized milk diet were significantly lower (P < 0.01) than plasma cholesterol concentration in rabbits fed the 0.1% cholesterol + boiled E. coprostanoligenes in 2% fat homogenized milk diet. Liver enzymes activities and major metabolites in plasma were not influenced by the bacterial treatments. Fecal excretion of cholesterol, coprostanol, sitosterol and bile acid in rabbits fed the 0.1% cholesterol + E. coprostanoligenes in 2% fat homogenized milk diet were greater at day 77 compared with that excreted by rabbits fed the 0.1% cholesterol + boiled E. coprostanoligenes in 2% fat homogenized milk diet. Fecal bile acid excretion was 1.9 times greater (P < 0.05) in rabbits fed the 0.1% cholesterol + live E. coprostanoligenes in 2% fat homogenized milk diet. Fecal coprostanol/cholesterol ratio of rabbits fed the 0.1% cholesterol + live E. coprostanoligenes in 2% fat homogenized milk diet at day 77 was greater 1.7 times greater than that of rabbits fed the 0.1% cholesterol + boiled E. coprostanoligenes in 2% fat homogenized milk diet. In s\immary oral administration of E. coprostanoligenes via milk decreased plasma cholesterol conversion of intestinal cholesterol to 59 coprostanol and increased excretion of cholesterol, coprostanol and bile acids. Therefore, milk may be used as food to deliver a hypocholesterolemic microbe to people. (Supported in part by Anderson Erickson Dairy Company, Iowa Dairy Products Association, and the Center for Redesigning Foods to Improve Nutrition) .

Use of Eubacterium coprostanoligenes to decrease plasma cholesterol concentration in hypercholesterolemic rabbits and the cholesterol content of fermented meats