English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The modified relative dose response (MRDR) assay is a minimally invasive method of detecting marginal vitamin A status. In the present study, the MRDR assay was performed four times in six well-nourished adults and in one male 5-yold child over a 7-month period. In all instances, assay ratios of dehydroretinol (DR) to retinol (R) were <0.030, the tentative cutoff value of "normal" for the MRDR assay in humans. The mean ratio for all time points for all individuals was 0.015 + 0.005, with a mean coefficient of variation of 27 + 13%. In a related experiment, both MRDR and conjunctival impression cytology (CIC) tests were conducted on nine adults and the same male child. All DR/R ratios were <0.02, and all CIC specimens were normal. Thus, the DR/R ratio in well-nourished individuals, although showing some variation, does not oscillate between abnormal and normal responses. Furthermore, the DR/R ratios and CIC patterns were fully concordant.

Refinement of the modified relative dose response (MRDR) assay as a method to assess vitamin A status of humans