Open AccessInvestigation of an emergent, tetracycline-resistant, abortifacient Campylobacter jejuni clone in a pregnant guinea pig model
Author(s) -
Eric Burrough
Publication year - 2011
Language(s) - English
Resource type - Dissertations/theses
DOI - 10.31274/etd-180810-581
Subject(s) - campylobacter jejuni , abortifacient , guinea pig , inoculation , pathogenicity , tetracycline , microbiology and biotechnology , biology , veterinary medicine , pregnancy , medicine , abortion , immunology , antibiotics , endocrinology , bacteria , genetics
Objective—To compare pathogenicity of an emergent abortifacient Campylobacter jejuni (IA3902) with reference strains after oral inoculation in pregnant guinea pigs. Animals—58 pregnant guinea pigs. Procedures—Twelve animals were challenged IP with Campylobacter jejuni IA3902 along with 5 sham-inoculated controls to confirm abortifacient potential. Once pathogenicity was confirmed, challenge via oral inoculation was performed whereby 12
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