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Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death among females worldwide.1 As per GLOBOCAN 2018 database, breast cancer ranks as the fifth leading cause of death (627000 deaths, 6.6%) and prognosis is considered to be relatively favourable in developed countries.2 In Nepal, breast cancer accounts for 11.6% of all the cancer related deaths in women, ranking third after cervical and lung cancers.3 Original Article

Correlation of histological grade with Estrogen, Progesterone and HER2/neu reactivity in breast cancer