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Antibiotics are lifesaving drugs in infections. They are categorized broadly into cell wall inhibitors, protein synthesis inhibitors and enzyme inhibitors. Amoxicillin belongs to cell wall inhibitors group of antibiotics. It is one of the widely prescribed antibiotics. It has adverse effects like diarrhea, hepatotoxicity and hypersensitivity. Along with these, recent findings have presented various effects in brain, heart, kidney and testes. Neurotoxic effects like depression, confusion, disorientation, somnolence, twitching, myoclonus, generalized tonic clonic seizures, status epilepticus were evidenced in different studies. The first three are well known adverse events whereas neurotoxicity is the recent finding.

Amoxicillin Induced Behavioral Neurotoxicity and Histopathological Changes in Organs of Albino Rats