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It has been estimated that of all congenital anomalies, prenatal infections alone account for 2 to 3%. TORCH infections are some of the most common infections associated with congenital anomalies. Most of the infections caused due to TORCH result mild maternal morbidity but may have serious fetal consequences and treatment on maternal infection frequently has no advantage on fetal outcome. Therefore, it is to be noted that once the maternal infection is recognized, clinicians should carry out the treatment of maternal disease The infection of Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV) and Herpes simplex virus (HSV) abbreviated as TORCH has remained a major problem in the women of childbearing age in Nepal. Nowadays, TORCH screening has been routine practice to monitor the plight of mother and growing fetus. Infections caused by TORCH and others agents like Chlamydia trachomatis, Treponema pallidum, Neisseria gonorrhoeae, and HIV are the major causes of Bad Obstetric History (BOH) (McCabe and Remington, 1988; Turbadkar et al, 2003). BOH implies previous unfavorable fetal outcomes in terms of two or more consecutive spontaneous abortions, early neonatal deaths, stillbirths, intrauterine fetal deaths, intrauterine growth retardations and congenital anomalies. Maternal infections transmissible in utero at various stages of gestation lead to recurrent pregnancy wastage. Infections caused by TORCH are the major cause of BOH (McCabe and Remington, 1988). Introduction lqe'jg ljZjljBfno

Toxoplasma, Rubella, Cytomegalo and Herpes Viral Antibody Level in Patients at National Public Health Laboratory (NPHL), Kathmandu