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Background: This prospective study was carried out in the Department of Pathology, University College Hospital, Ibadan, Nigeria between December 2008 and April 2010 with an aim to determine the frequency of lymphocytic thyroiditis at autopsy. Method: Haematoxylin and eosin stained slides of thyroid glands from 107 individuals (65 males and 42 females) who died from non-thyroid related diseases were reviewed and categorised using Williams and Doniach’s criteria. Results: Lymphocytic infiltration occurred in ten (9.3%) cases, including 8 males and 2 females. The inflammation was Grade 1 in seven cases, Grade 2 in two cases and Grade 3 in one case (Hashimoto thyroiditis). Moderate and severe grades of inflammation were restricted to subjects aged 40 years and above (p = 0.01) and were only observed in patients who died either from infective illnesses or unnatural/violent causes. Conclusion: The results of this study suggest that the prevalence of thyroiditis in Ibadan has remained relatively constant in the last two decades. It is suggested that prevalence of marker of subclinical autoimmune disease, which thyroiditis represents, has not increased in Ibadan over the last two decades. The results of this study suggest that the prevalence of thyroiditis in Ibadan has remained relatively constant in the last two decades. It is suggested that prevalence of marker of subclinical autoimmune disease, which thyroiditis represents, has not increased in Ibadan over the last two decades.

Lymphocytic thyroiditis at university college hospital, Ibadan, Nigeria - a prospective post-mortem study