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The erythrocyte binding antigen 175 kDa (EBA-175) of Plasmodium falciparum is one of the major ligands for red blood cell invasion by merozoites. EBA-175 is a dimorphic antigen but the role that dimorphism plays in host parasite interaction is not fully understood. In this study, we sought to determine the distribution of EBA-175 genotypes and its pathogenetic influence.

Imbalanced Distribution of Plasmodium falciparum EBA-175 Genotypes Related to Clinical Status in Children from Bakoumba, Gabon