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Huntington's disease (HD)(MIM:143100) is an severe autosomal dominant neurodegenerative disease caused by the dynamic expansion of CAG trinucleotides (&gt; 35) in the HTT gene [Genomic Coordinates- (GRCh38):4:3,074,680-3,243,959].

Distribution of the HTT Gene A1 and A2 Haplotypes Worldwide: A Systematic Review