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The aim of this study was to investigate the oxidative, hemodynamic, and analgesic effects of local lidocaine infiltration, or intravenous (IV) fentanyl injection, or a combination of lidocaine and IV fentanyl during head fixation in a 3-pin headrest in patients undergoing elective craniotomy.

Efficacy of Fentanyl and/or Lidocaine on Total Antioxidants and Total Oxidants During Craniotomy