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Background and objective: The present study assesses the relationship between hyperuricemia and pulse pressure (PP) in non-diabetic Korean adults.Material and methods: Data from 5122 subjects (2251 men and 2871 women) in the seventh Korean National Health and Nutrition Examination Survey (KNHANES VII-2, 2017) were analyzed.Results: Systolic blood pressure (SBP) and PP were signicant factors determining the odds ratios (ORs) for hyperuricemia (uric acid ≥7.0 mg/dL in men or ≥6.0 mg/dL in women) in men and the overall population. In women, SBP, diastolic blood pressure (DBP), and PP were not signicant factors determining the OR for hyperuricemia. After adjusting for related variables, the OR of hyperuricemia was signicantly higher in the high PP group (PP &gt;60.0 mmHg) for men (OR, 1.760; 95% condence interval [CI], 1.152--2.688) and the overall population (OR, 1.557; 95% CI, 1.132--2.140) compared with the normal PP group, but this trend was not seen in women (OR, 1.060; 95% CI, 0.646--1.740).Conclusions: Hyperuricemia was positively associated with PP in non-diabetic Korean men but not in women.

Sex-speciﬁc in the relationship between hyperuricemia and pulse pressure in non-diabetic Korean adults: the 2017 Korean National Health and Nutrition Examination Survey