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The nature of the doctor-patient interaction significantly affects the trust in their relationship. Barriers in communication which ignore the emotional needs of patients reduce patient trust in the doctor, as well as challenge the delivery of patient-centered-care, the preferred approach of care. Based on previously acknowledged determinants of patient trust in the patient-doctor relationship, we identified two patient mind-set segments which supersede age and gender. Patients in one mindset expect their doctor to greet them respectfully, to be empathic, to listen carefully without interrupting, and in the end feel that their doctor understands them. Patients in the second mind-set segment expect the doctor to enhance their internal locus of control. This second mind-set wants the doctor to educate them, providing clear, relevant, tailored, information and ensuring that they understand the information. This second mind-set wants the doctor to let them feel comfortable asking questions about what they didn’t understand, and walk them through a change process, by steps, towards self-management of their disease.

Cartography of Doctor-Patient Relationship: A Mind- Genomics Exploratory Study about the Public’s Response to Patient-Centered-Care