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Decreased estrogenization in post-menopausal women causes changes in the lower urinary tract. Vulvovaginal atrophy (VVA) is a pathological condition resulting from those changes. VVA has a negative effect on the quality of life therefore prompting a search for well tolerated therapeutic options. This article was aimed to evaluate whether the participation of the patient in the choice of the therapy may improve the adherence to the treatment. In particular, there are two distinct pharmaceutical forms in vaginal cream and pessaries based on the Triticum vulgare extract (TVE) for the treatment of post-menopausal VVA. We examined the clinical reports of 48 women with VVA who chose to be treated with Fitostimoline® 20% vaginal cream (based on TVE, 2-phenoxyethanol; glycerine; white vaseline; sodium cetyl stearyl sulfate; cetyl stearyl alcohol; decyl oiled; methyl parahydroxybenzoate; propyl parahydroxybenzoate; purified water. Produced by Farmaceutici Damor, Naples, Italy) and 43 who preferred Fitostimoline® 600 mg pessaries (based on TVE, 2-phenoxyethanol; macrogol 400; macrogol 1500; macrogol 12000. Produced by Farmaceutici Damor, Naples, Italy) for a 3-month treatment. Signs and symptoms of VVA were available during the baseline and after 12 and 90-day treatment visits.

Treatment of Vaginal Atrophy with the Aqueous Extract of Triticum vulgare: Comparison between Different Pharmaceutical Forms