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A wanted pregnancy is typically viewed as a time filled with excitement, but the uncertainty about its outcome can be quite worrisome to the patient. Parental concern often begins from the first trimester. Currently, significant data exist regarding normal and abnormal ultrasonographic measurements of the gestational sac (GS), yolk sac (YS), crown-rump length (CRL) in early gestations [1,2]. These parameters have been studied for the dual purpose of establishing standardized parameters for each gestational age and predicting early pregnancy failure [3-5]. The yolk sac is the primary source of nutrition, metabolic, immunologic, excretory, and hematopoietic functions prior to placental development, and the CRL is known to accurately correlate with gestational age during the first trimester of pregnancy [6-10]. While these measurements have typically been looked at individually, the current understanding of the relationships between them is limited. The primary purpose of this study is to establish normal values for the ratio of the fetal Crown-Rump Length (CRL) to the yolk sac (YS) diameter during the first trimester of normal pregnancy and determine whether it correlates with gestational age.

The Relationship of the Fetal Crown-Rump Length to the Yolk Sac Diameter in Normal Pregnancy