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Term “Cognition” is defined in various ways by researchers a  combination of processes uses to manage information, including attention, acquisition, encoding of material, rehearsal and praxis (skilled motor behaviors) are important determinants of memory ability. In daily life, persons regularly complain that their memory is insufficient or that they cannot give attention cognitively challenging circumstances (Whitehouse et al., 1997).Cognitive dysfunction due to pathologic condition like neurodegenerative diseases, anxiety, depression, hypoxia, cardiovascular surgery, tumors and normal aging. Numerous neuromodulators play significance role in learning and memory are acetylcholine, dopamine, serotonin, epinephrine, norepinephrine, histamine, neuropeptides, angiotensin converting enzymes, platelets activating factor, insulin, oxygen free radical, and neurotrophic factors etc.

Sphaeranthus indicus enhances memory and protects against amnesia in rodent models