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Schiff base named after Hugo Schiff. Schiff bases were form by condensation between aldehydes and amines. Schiff bases are containing C=N moiety which possess broad spectrum of biological activity and when they incorporated with metals in the form of metal-complexes then the degree of biological activity enhances. Schiff bases and amides derived from various heterocyclic compounds shows broad range of biological activities such as anticancer, antiviral, antimicrobial, anticonvulsant, antidepressant, angiotension-II receptor antagonist, anti-inflammatory and anti-glycation activity. So far, modifications of the Schiff bases have improved potency and toxicity decreased.

Synthesis and stability constant of schiff’s bases of triazole