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Neuronal function and increase in neurodegeneration is the result of consequence of memory impairment during aging, may be due to accumulation of oxidative damage and impairment of antioxidant defense system ( . At old age Haddadi et al., 2014) and neurodegenerative disorders, cognitive impairment is a prominent feature) ( . Alzheimer's disease Sharma et al., 2008) (AD) is a neurodegenerative disorder expressed by progressive loss of memory and cognitive impairment. AD prevalence is approximately 1% between 65 and 69 years and is higher than 50% in individuals above 95 years ( . As said Vasto et al., 2008) with increasing age, the demage of the cerebral neurons is one of the commonest and vital causes for Alzheimer's like dementia (Agarwal et al., 2002). Neuronal loss leads to memory loss or impairment that result in progressive disability and eventual incapacitation (Negishi and Kawahara, 2008; Hung et al., 2008).

Menthol causes reduction of Scopolamine induced Glutamatergic neurotoxicity and cognitive deficits