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Histochemical examination of fingerlings and adults of freshwater teleost Oreochromis mossambicus (Trewavas) exposed to sublethal concentration of HgCl2 (0.15 mg/l) for 30 days revealed considerable uptake of mercury by their respective intestines. Simultaneous co-administration of Essential phospholipids (EPL) along with food to the fishes, significantly supressed mercury uptake by the intestinal tissues, except the goblet cells which were still loaded with Hg in both stages. Due to accumulated mercury visible histopathological damage was seen in muscle layers, lamina propria and basement membrane of columnar cells. No noticeable damage in intestine was seen, when EPL was simultaneously fed to fishes along with HgCl2 exposure. Results suggest that EPL plays prophylactic role against metal uptake and structural damage in fish intestine exposed to inorganic mercury.

Essential phospholipids protection against mercury uptake and histopathological changes in the intestine of fish, Oreochromis mossambicus (Trewavas)