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Phytoremediation is an alternative to traditional chemical and ways of treating polluted soils .The currentstudy was carried out to investigate the phytoremediationofsoil contaminated withnickel (Ni)byLepidium sativum.Soilsamples from0to10 cm depth werecollected.Lepidium sativumwas transplanted in pots containing 5 kg ofthe collectedsoils.Central composite design and response surface methodology were employed in order to illustrate the nature of the response surface in the experimental design andexplain the optimal conditions of the independent variables. Different

Phytoremediation of Soil Contaminated with Nickel by Lepidium sativum; Optimization by Response Surface methodology