A Review on Mucoadhesive Microspheres as an Optimised Targeted Drug Delivery System
Author(s) -
Sandhya Sharma,
Moumita Barman,
Neelam Singh,
Abhishek Bhardwaj,
Rosaline Mishra,
Monika C. Singh,
Prasoon Kumar Saxena
Publication year - 2018
Publication title -
indian journal of pharmaceutical and biological research
Language(s) - English
Resource type - Journals
ISSN - 2320-9267
DOI - 10.30750/ijpbr.6.4.1
Subject(s) - bioavailability , mucoadhesion , drug delivery , microsphere , buccal administration , absorption (acoustics) , delivery system , drug , nasal administration , dosage form , pharmacology , medicine , drug carrier , materials science , nanotechnology , chemical engineering , composite material , engineering
Mucoadhesive microspheres play an imperative job in the drug delivery system due to their small size and other effective properties. It is utilized as a carrier for medication. Mucoadhesive microspheres delayed the residence time at the site of utilization or absorption and facilitate an intimate contact with the underlying absorption surface and in this way enhanced therapeutic performance of medications. It can also enhanced bioavailability and efficient absorption of the medications because of a high surface to volume proportion, a considerably more intimate contact with the mucus layer, controlled and sustained release of medicamentfrom dosage form and specific targetingmedications to the retention site. These can be created for oral, buccal, nasal, ocular, rectal and vaginal for either systemic or local effects.
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