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6-pyridin-4-yl-2, 3-dihydro-1H-pyridazin-4-one derivatives were synthesized by a simple method. The isonicotinicacid hydrazide was made to react with acetaldehyde and acetone. This results into the formation of the respectivehydrazones. These hydrazones formed were cyclized to the pyridazine derivatives. All synthesized compounds weresubjected to antimicrobial activity.

Synthesis and microbial screening of 6-pyridin-4-yl-2, 3-dihydro-1Hpyridazin-4-one derivatives