English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

53 Introduction 54 Methods 56 Dissection 56 Staining of neuronal membranes 57 Retrograde labeling 57 Optical imaging and picture processing 58 Figures and data analysis 59 Results 61 xi General structure of the commissural ganglion 61 Descending projection neuron distribution in the commissural ganglion 64 Organization of projection neuron clusters 66 Spatial preferences of dPNs 69 Discussion 72 The commissural ganglia: Centers for controlling divergent neuronal outputs 72 Clustering and variability of projection neuron location 75 Preferential locations of projection neurons 78 REFERENCES 82 FIGURES 93 CHAPTER III: A PREMOTOR NETWORK ENCODES MULTIMODAL INFORMATION AND CONTROLS MOTOR OUTPUT VIA A COMBINATORIAL CODE 102 Abstract 102 Introduction 102 Methods 106 Animals 106 Solutions and reagents 107 Anterograde tracing of sensory pathways 107 Application of a voltage-sensitive dye 107 Stimulation of sensory nerve pathways 108 Optical imaging 108 Extracellular nerve recordings 109 xii Data analysis and figure construction 109 Imaging analysis 110 Motor pattern analysis 113 Results 113 The CoG premotor region processes information from multiple sensory modalities 113 Similarities in the premotor spike frequency distributions between modalities contradict a network rate code 117 Modality-specific neurons and distinct premotor network activation support a combinatorial code for multimodal representation 118 The bimodal sensory condition elicits mechanosensory-like premotor network activation and participation 120 CoG premotor network activation and participation contribute to downstream changes in pyloric motor output 122 Discussion 126 Potential mechanisms for the encoding of multimodal sensory information 126 A combinatorial code of premotor network activation and participation determines motor output 128 The bimodal condition is encoded in a new combination of premotor activities 131 Implications for multimodal encoding and motor pattern selection in higher order brain areas 134 REFERENCES 136 FIGURES 147 xiii CHAPTER I FIGURES Figure Page 1. Schematic overview of the stomatogastric nervous system 44 2. RH795 stains through the ganglion sheath and allows visualization of soma location 45 3. RH795 staining in the stomatogastric nervous system of the crab 46 4. Desheathing causes subtle changes in neuronal activity 48 5. Optical imaging through the ganglion sheath 50 6. Repetitive staining permits long-term experiments 51 7. RH795 allows the simultaneous recording of gastric mill neurons through the ganglion sheath 52

A Combinatorial Premotor Neural Code: Transformation Of Sensory Information Into Meaningful Rhythmic Motor Output By A Network Of Heterogeneous Modulatory Neurons