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Background: Adiposity assessment plays an important role in coronary artery disease (CAD) prevention. One of the adiposity parameter in major CAD management guideline is waist to height ratio (WHtR). Adiposity promotes the pathogenesis of coronary atherosclerosis by involving adipokines released by adipose tissue. Leptin is obesity identic adipokine which is used as prognostic predictor of cardiovascular event. This study aims to analyze correlation between WHtR and leptin serum level. Method: A cross sectional study was performed to 37 stable CAD patients undergone elective coronary angiography in Heart Catheterization Laboratory Dr Hasan Sadikin Hospital, Bandung, West java in July 2014 Results: Mean age of the subjects was 56.7± 9.12 years old with mean age of men (n=32) and women (n=5) were 55.9±9.47 years old and 62±3.54 years old consecutively. There were 30 (81%) subjects classified as obese (WHtR≥0.5) with mean WHtR 0.54±0,06. Median value of leptin serum was 8599.90 pg/ml (780-36929.3 pg/ml). Based on rank-spearman correlation test, a positive moderate correlation was significantly found between WHtR and Leptin serum level (Spearman’s rho = 0.5, p= 0.001). Conclusion: Positive correlation was found between WHtR and leptin serum level. Hence, WHtR might be useful as indicator of leptin serum level which has been used as a prognostic biomarker in CAD patients

Correlation of Waist to Height Ratio with Leptin Serum Level in Coronary Artery Disease