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The present study was conducted to study the in vitro antioxidant, antiulcer and analgesic activities of dichloromethane fraction (DCMF) of stem barks from Boswelli dalzielii Hutch using different models in rats and mice. The antioxidant activity has been evaluated using β-carotene-linoleic acid system and lipid peroxidation and which showed antioxidant capacities. Antiulcer activity of dichloromethane fraction (DCMF) of stem barks from Boswelli dalzielii Hutch was studied in rats by administration of ethanol-induced method and by pyloric ligation method. The analgesic activity of dichloromethane fraction (DCMF) of stem barks from Boswelli dalzielii Hutch (Burseraceae) was tested using the model of acetic acid induced writhing in mice. The present study exhibit maximum radical scavenging activity and has positive effects in a dose dependent manner against ulcer induced by pyloric ligation-induced ulcers and cytoprotective model and analgesic activity using the model of acetic acid induced writhing in mice. The obtained results allow justifying the traditional uses of Boswelli dalzielii Hutch. This present study has clearly supported the utilization of Boswelli dalzielii Hutch in Burkina Faso traditional medicine.

In vitro antioxidant capacity and in vivo anti-ulcer and analgesic potentials of dichloromethane fraction of stem barks from Boswelli dalzielii Hutch