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Abnormal production of thyroid hormones has been found in 44.8% of adolescent children living in raions of Kyiv region bordering the Chernobyl exclusion zone. Moreover, a change in the genome of folate cycle has been noted in 97.0% of cases. Many of these children have high blood levels of homocysteine. It is important to determine associations of folate cycle genome with the production of pituitary-thyroid axis hormones in order to investigate the pathogenesis of thyroid diseases in children from districts contaminated with radionuclides as a result of the Chernobyl nuclear power plant accident. The purpose of the study is to determine the role of folate cycle genome in the formation of associations between the thyroid-stimulating hormone of

THE ROLE OF THE FOLATE CYCLE GENOME IN ESTABLISHING LINKS BETWEEN HOMOCYSTEINE, HORMONES OF THE PITUITARY-THYROID AXIS AND VITAMINS OF THE «В» GROUP IN CHILDREN FROM THE DISTRICTS, BORDERING THE CHERNOBYL EXCLUSION ZONE