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A flavonoid compound namely kaemferol had been separated from the acetone extract of the silver fern (Pityrogramma calomelanos). It was obtained as yellow needles crystal with m.p. of 271-273 oC. Determination of its structure was conducted by the spectroscopic method and by comparison with reported literature data. Based on the carbon clearance method, isolated flavonoid showed immunostimulant activity with phagocytosis index of 1.846. Keywords—Pityrogramma calomelanos, kaemferol, immunostimulat activity

Immunostimulant Activity of Flavonoid Isolated from The Acetone Extract of Silver Fern (Pityrogramma calomelanos)