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To the turbulence induced by local voltage oscillations during repolarizing phase of the cardiac action potential, the effects of current pacing and electrical field were investigated to reveal their feasibilities in elimination of the turbulence. A local pathological 2-dimensional tissue including 401 × 401 myocytes was developed on the basis of LR91 single cell mathematical model. The myocytes at the central 20 × 20 region was characterized with voltage oscillations by increasing time constant of K gating variable and maximum conductance of Ca current. The cross field method was used to induce spiral waves that degraded to turbulence-like fibrillation under the influence of pathological region. The defibrillation model was created by introducing the current and electrical field terms, respectively. The computer simulation results showed that local current pacing had no significant effects on the turbulence, but after subsequent application of electrical field, the turbulence was depressed around 240 ms. Current pacing on the whole tissue was able to completely suppress wave breakup at 625 ms, but with the execution of electrical field, the elimination time reduced to 240 ms. Therefore, current pacing together with electrical field has greater effects on electrical activities of the tissue. It promotes the process to suppress the wave breakup, thus eliminating the turbulence-like fibrillation. Keywords-turbulence; current pacing; electrical field; action potential mathematical model; computer simulations

Effects of Current Pacing and Electrical Field on The Turbulence Induced by Voltage Oscillations in Hearts