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Objective: To investigate the occurrence of exercise stress gastric ulcer during motilin hormone content and expression of HSP70 and dangshen on Exercise Stress Ulcer Prevention effect and its mechanism. Methods: 30 adult SD rats were divided into three groups, each 10, divided into the control group, movement control, movement dosing group, the establishment of Exercise Stress Gastric Ulcer Model. Each group of rats gastric mucosa pathological damage index scoring by immunohistochemical staining gastric mucosa HSP70 expression; gastric tissue content preparation, testing motilin. Results: Compared with quiet group, gastric motility group organization motilin levels were significantly increased, slightly increased HSP70 expression; compared with motion control, dosing rats gastric tissue motilin levels were significantly decline, HSP70 expression increased further. Conclusion: Codonopsis can prevent exercise stress gastric ulcer, the protective mechanism may reduce gastric tissue in rats motilin content and increase the expression of HSP70 related. All organisms under stress conditions can be synthesized in a highly conserved protective protein that is HSPs, especially high-intensity sports exhaustive exercise as a source of stress, causing physiological functions of various organ systems of the human body changes over the past decade, people express when the body motion stress HSPs conducted experimental studies, have found that the expression of HSPs[1] in the brain, liver, heart, skeletal muscle, spleen and blood cells and other parts of the body after exercise , HSP70 family is the most important one of its kind HSP protect the gastric mucosa, but there are no studies on exercise and stomach tissues of HSP70 relations. Numerous studies show that high intensity exhaustive exercise, especially as a strong source of stress, the blood flow to reduce the gastrointestinal tract, increased production of free radicals, lipid peroxidation increased production, will eventually cause gastric mucosal protective effect and injury of loss of balance, causing Exercise Stress Ulcer[2]. Clinical studies have shown dangshen, spleen, stomach, regulate gastrointestinal function, antioxidant and immunomodulatory effects[3]. Expression and motilin content in this experiment study the role of HSP70 in gastric stress ulcer in sport and in prevention of Codonopsis. 1 Materials and Methods 1.1 Animals SD adult male rats, weighing 240-300g, Xi'an Jiaotong University Laboratory Animal Center. 1.2 Reagents and Instruments Codonopsis purchased from Shaanxi Institute of Chinese Medicine; Motilin radioimmunoassay kit (purchased from the East Asian Institute of Technology, People's Liberation Army General Hospital immunity). 1.3 Movement to establish stress ulcer model Zhao Jingguo study combining exercise stress ulcer model[3]and[4]Bedford motion model, and ethology performance sports model as the basis for the establishment of specific training programs are shown in Table. Movement model: Full training for six weeks, four weeks of basic training before the first five weeks into the high-intensity training (exercise intensity according to Bedford[12]rat body weight / VO rat model of incremental exercise load training regression equations established be determined). 2nd International Conference on Machinery, Materials Engineering, Chemical Engineering and Biotechnology (MMECEB 2015) © 2016. The authors Published by Atlantis Press 660 The first six weeks of the first five weeks of training load is substantially the same, but differ when the last training, according to the following exhaustive exercise program: The 35 m / min running speed, until the animal can not keep rats at a predetermined speed, rats buttocks pressure in the cage wall, hind legs dragging the belt with the rotation after 30 seconds, when the stimulus driven brush VI I invalid, reduce exercise load (by the → grade load), continues to move to when the load level sport anim I als failed adhere to the same level load running speed, has retained more than 3 times from 2/3 end of the runway , signs failure, stimulate expulsion invalid, the criteria for judging exhaustion. Table 1 List of Laboratory Animal Movement programme Week speed(m/min) Time(min/d) Distance(m) Load Level 1 15 25 375 Grade load I 2 20 30 600 Grade II load 3 25 35 875 Grade III load 4 30 4

Codonopsis on Exercise Stress Ulcer rat stomach tissues and motilin content on HSP70 expression