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This paper used parallel test of single factor to investigate feed ratio of inclusion compound, drying method, the volatilization temperature of ethanol for Pulsatilla Chinensis (Bunge) Regel total saponins-HP-β-CD inclusion compound. The results showed that the best preparation process of inclusion compound was as following: the feed ratio of Pulsatilla total saponin extract and HP-β-CD was 1:1; After the Pulsatilla total saponins extract with ethanol solution was dropwise added to the HP-β-CD aqueous solution, the mixed solution was continuously stirred for 6h at 60C and was freeze-dried for 12h. The preparation process for Pulsatilla Chinensis (Bunge) Regel total saponins-HP-β-CD inclusion compound was simple and it is helpful to improve the drug dissolution.

Investigation of HP- -CD Inclusion Compound Preparation Process for Pulsatilla Chinensis (Bunge) Regel Total Saponins