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E. coli is “wise” enough to take suitable responding time, and suitable responding behaviors, when facing different kinds and intensities of stimulations. In a network of glycogen metabolism, a shorter time stimuli result in the post translation level reactions for quicker response, and a longer time stimuli will activate more time consuming the central dogma level reactions. In addition, different intensities of signals caused by different actions was illustrated by using gene products expression system based on ppGpp concentration.

Intelligent mechanisms in E. coli in processing carbon sources