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Ascariasis is known as “soil transmitted helminths” which persons were infected by ingesting eggs were passed in the feces. The most prevalence of Ascariasis in school children are more than 30%, with resultant impairment in growth retardation, intellectual, and cognitive development. The purpose of this research was to determine the anthelminthic effectivity of Gandarusa Leaves Infusion (GLI), Kapuk Seed Infusion (KSI) were the same as pyrantelpamoat as against female Ascarissuum in vitro. Methods of the research was true laboratory experimental, using 1200 female worms of Ascarissuum, which GLI and KSI treatment were divided into 8 treatment groups (GLI1, GLI2, GLI3,GLI4 and KSI1, KSI2, KSI3, KSI4), one negative control with NaCl, positive control with pyrantelpamoat. The treatment groups were incubated at 37C for 3 hours. The data measured were number of paralyzed and dead worms. Data was analyzed using ANOVA, followed by Tukey HSD test α = 0.05. The results showed that the highest percentage number of paralyzed and dead worms on GLI 4 was 70%, on KSI4 was 40.83%, GLI 4 was not significant (p>0.05) with pirantelpamoat. GLI and KSI contain various compound such as alkaloid, tannin and saponin. Conclusion GSI 4 had an anthelminthic effectivity the same as with pirantelpamoat.

The Anthelminthic Effectivity of Gandarusa Leaves (Justiciagendarussa Burm. F.) Infusion And Kapok Seed Infusion (Ceibapentandra L.) Against Female Ascarissuum In Vitro