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The Belt and Road (B&R initiative) is a comprehensive initiative to deepen reform and opening up, and is of great significance for the development of in-depth economic globalization of China. And large-scale innovation and entrepreneurship talents are the key factors in promoting the economic globalization. Western China, as the starting point of Silk Road, should proactively adapt to the need of B&R initiative. As the base of higher innovation and entrepreneurship talents, Western colleges and universities in China should give full play to the cultivation of innovative and entrepreneurial talents, fully understand the significance of innovation and entrepreneurship of B&R initiative, accurately grasp the compatibility features between B&R initiative and innovation and entrepreneurship education, and finally achieve the role of innovation and entrepreneurship education in fostering talents from aspects such as concept changing, region basing, quality improving, policy implementing, and system perfecting. Keywords—B&R initiative; Western regions; Innovation and entrepreneurship education; Route

Route Construction of Innovation and Entrepreneurship Education Development in Universities of Western China against the Belt and Road Initiative