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The article examines the pathogenetic features of the rearrangement of body functional state, against the background of psychological stress. At the present time the steady increasing of flow of information and emotional stress lead to load increasу of the central nervous system. It is necessary to increase the nutrient substrate – glucose and, for its aerobic catabolism the necessary amount of oxygen, to meet the intensification of the activity of the сentral nervous system. The increasing of energy costs of the central nervous system is accompanied by anticipation, which leading to change in eating behavior, and turning on a stress-hunger-food mechanism. Above mentioned factors lead to body weight increasing, and respectively, to increasing of the absolute circulating blood volume. At the same time, the relative circulating blood volume (ml/kg body weight) decreases, which leads to a shortage of blood coming to vital organs, including the central nervous system. Blood deficiency compensated by centralizing blood circulation, which is achieved by peripheral vascular spasm. In addition, there is psychological stress affect human body, that is constantly present in the modern lifestyle. Chronic psychological stress, leading to permanent activity of the sympathetic-adrenal system, is a concomitant factor of peripheral vascular spasm. Against this background, the conditions for the development of hypertension are created.

Pathogenetical Peculiarities of Arterial Hypertension with Weight Increasing on Psychological Stress Background