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Negative pressure wound therapy(NPWT) utilizes foam dressings to create an optimal healing environment. The anti-adhesion material was important for the clinic application of NPWT treatment. Polyvinyl alcohol (PVA) foam dressing could be considered as a good anti-adhesion material for NPWT treatment. An anti-adhesion extra thin foam dressing with good mechanical property would be a potential medical device for NPWT treatment. A series of anti-adhesion polyvinyl alcohol (PVA) extra thin foam dressings with different macroporosities and thickness of 1.5 mm were designed and prepared. Mechanical property of the resulting extra thin foam dressings was determined. Preclinical evaluation of new designed antiadhesion extra thin PVA foam dressings could be established by determining water morphology, water permeability, macroporosity, mechanical property of resulting samples. Keywords—PVA; foam; matrix

Design and Preparation of Novel Anti-adhesion Extra Thin Polyvinyl Alcohol Foam Dressings for NPWT via a Combined Procedure of Ultra Precision Machining and Super Clean Air-foaming