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Objective: To optimize the extraction process of flavonoids in mollugo pentaphylla with microwave-ultrasonic extraction combination to semi-bionic technology by the response surface method. Methods: With the yield of flavonoids as response value, Extraction Process conditions of flavonoids in Mollugo Pentaphylla were investigated by the method of Box-Benhnken to analyze experiment. Results: The fitting degree of the regression model is high, and the optimum technological conditions were as follows, the material liquid ratio 1:30, microwave power 200 W, extraction time 60s, and the ethanol concentration 60%. Conclusion: The microwave-ultrasonic extraction with semi-bionic technology can be used for the extracting of flavonoids in mollugo pentaphylla.

Study on Extraction Process of Flavonoids in Mollugo Pentaphylla by Microwave-ultrasonic Extraction with Semi-bionic Technology