English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Propanediol (1,3-PD) is an important chemical intermediate in manufacturing polyethers, polyurethanes and polyesters. Production of 1,3-PD by microbial fermentation has attracted increasingly attention of researchers. In this study, deletion mutant of K.pneumoniae HD-1 constructed by knocking out lactate dehydrogenase (LDH) gene in our previous work was cultivated in fermentation medium utilizing glucose as carton source and original strain K.pneumoniae were simultaneously used as the control strain under absolutely the same conditions and their capability of 1,3-PD production were compared. The results showed that an increase of 19.98%, 20%, and 20.19% of 1,3-PD titer, productivity, and yield, respectively were obtained from K.pneumoniae HD-1. Obviously it can be inferred that the ability in the production of 1,3-PD of the K.pneumoniae HD-1was better than that of the K.pneumoniae, therefore it could be a promising strain for 1,3-PD production in the further study of industrialized production. Keywords-K.pneumoniae; lactate dehydrogenase; 1,3-

Deletion of Lactate Dehydrogenase in Klebsiella Pneumoniae to Enhance 1,3-Propanediol Production