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Giving the wrong medication to the patient can cause problems such as the trauma of taking the drug, the patient's disability, and even death. The provision of nursing services by standard operating procedures (SOP) greatly helps nurses to achieve quality nursing care. Nurses are required to be able to administer drugs accordingly and must pay attention to the principle of six true namely true medicine, correct dosage, correct method (route), correct time, correct patient, and correct documentation. The purpose of this study was to determine what factors influence adherence in drug administrationin terms of characteristics (age, sex), fatigue, education level, personality, workload, and leadership style of the head of the care room. This research is a quantitative study with a descriptive correlation design with a crosssectional approach. Factors that influence nurses' compliance in applying the six principles of correct drug delivery are workload (0,000), leadership style (0.006), and personality (0,000). While unrelated factors are fatigue (0.091), education (0.166), age (0.906), and gender (0.072). Keywords— Nurse Compliance, Six Correct Drug Administration, Patient Safety

Factors Influencing Nurse Compliance in Applying the Six Principles of Drug Administration at RSUD Wates