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--Preimplantation genetic diagnosis (PGD) is an important method for the identification chromosomal abnormalities and genes responsible for genetic defects in embryos that are created through in vitro fertilization before pregnancy. This technique can screen sex and genetic abnormalities to avoid the implantation of defective embryos. However, PGD can potentially raises ethical issues such as the embryos deselection, sex selection, savior siblings, and eugenics. PGD is used to select the best embryos in terms of genetic profiles. This raises the potential of embryos that are not either discarded or donated to science. This selection discriminates people with disabilities. It also poses a dilemma in view of the Hippocratic oath that every doctor should value life from conception. PGD can find out the sex and diseases that may be related (X-linked disorder), so often there is a demand to change sex so that the embryo is not affected by the disease. The problem is if the demand by parents who want a child of a certain sex as family balancing. PGD is also used to save siblings (savior siblings). PGD is only for screening for serious genetic diseases, but has the potential to develop into modern eugenics that design children as desired, such as gender, height, beauty, intelligence, and hearing; according to the demands of parents who want the best for their children Regulation and further studies from various disciplines are needed to prevent potential ethical and legal problems.

Preimplantation Genetics Diagnosis: Ethical and Legal Aspects