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Brief counseling by Pharmacist (BCP) and selfevaluation drug use sheet (SEDUS) may improve patients' behavioral changes, thereby improve blood pressure levels. The study aims to determine the effect of BCP and self-SEDUS on blood pressure and blood glucose level of outpatients with diabetes mellitus and hypertension complication (DMHC) with standard therapy at Polyclinic of Internal Medicine in Public Hospital, Bantul, Yogyakarta. We conducted a quasiexperimental study with prospective data collection during March-May 2017. A total of 99 DMHC who met the eligibility criteria were divided into three groups, 33 patients each group, respectively. The control group received standard therapy with routine drug information from hospital Pharmacist. The treatment group 1, received standard therapy and BC from the pharmacist (BCP) counselor. The treatment group 2, received conventional therapy and BCP combination with SEDUS. We presented demographic and clinical characteristic, descriptively. We analyzed the mean difference of blood pressure and blood glucose level between the group with one way-ANOVA and multiple comparisons. Result: The Posttreatment systolic blood pressure (PTSBP) in the treatment groups I and II were lower than PTSBP in the control group (p<0.05). The post-treatment blood sugar levels (PTBGL) in the treatment groups were lower than PTBGL in the control group (p<0.05). BCP combination with SEDUS intervention for one month reduced SBP and blood sugar levels (p< 0.05). Conclusion: brief Counselling and SEDUS in patients DMHC at Public Hospital, Bantul, Yogyakarta improved effectivity of anti-hypertension and anti-diabetes Mellitus drug. Keywords—diabetes mellitus and hypertension complications, brief counseling, self-evaluation drug use, medication behavior change

Brief Counselling with Self-evaluation Drug Use Sheet to Improve the effectivity of Drug Therapy in Diabetes Mellitus with Hypertension Complication Outpatients