English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background:Apolipoprotein M (ApoM) is bound to high-density lipoprotein (HDL) in plasma,and HDL has anticoagulation effects. However, the association between ApoM and biomarkers of coagulation was unclear. Therefore,we investigated relationships between ApoM and biomarkers of coagulation. Methods: Serum samples from 233 Japanese participants including with diabetes mellitus, hypertension, dyslipidemia, or healthy controls were analyzed. Serum ApoM levels were measured using Enzyme-Linked Immuno-Sorbent Assay(ELISA). Results:Analysis of all 233 participants showed that ApoM levels were positively correlated with age(r=0.284, p<0.001),total cholesterol (TC;r=0.477,p<0.001),HDL-cholesterol (HDL-C;r=0.234,p<0.001) and lowdensity lipoprotein cholesterol (LDL-C;r=0.331,p<0.001). Higher ApoM levels were correlated with shorter activated partial thromboplastin time(APTT;r=-0.226,p=0.001)and prothrombin time(PT,%;r=0.326,p< 0.001). Separate analysis of the 115 healthy controls showed that ApoM levels were positively correlated with age, TC,HDL-C and LDL-C,and higher ApoM levels were correlated with shorter PT. Conclusion:Serum levels of ApoM may influence biomarkers of coagulation.

Serum Apolipoprotein M Levels are Correlated with Biomarkers of Coagulation