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In recent years, new α-particle-, β - -particle-, and Auger electron-emitting radiometals-such as 67 Cu, 47 Sc, 166 Ho, 161 Tb, 149 Tb, 212 Pb/ 212 Bi, 225 Ac, and 213 Bi-have been produced and evaluated (pre)clinically for therapeutic purposes. In this short review article, the most important routes of production of these radiometals are critically discussed, as are examples of their application in preclinical and clinical studies.

journal of nuclear medicine

Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β−-Particle, and Auger Electron Emitters