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18 F-(E)-N-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4'methylphenyl)nortropane ( 18 F-FE-PE2I) is a newly developed dopamine transporter (DAT) PET radioligand. Full quantification methods rely on dynamic acquisition of 18 F-FE-PE2I, but in a clinical setting a simplified protocol is preferable. The aims of this study were to identify the optimal acquisition time window for 18 F-FE-PE2I and to validate the specific binding ratio (SBR) as a simplified quantification method.

the journal of nuclear medicine

Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using <sup>18</sup>F-FE-PE2I in Healthy Controls and Parkinson Disease Patients

Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using 18F-FE-PE2I in Healthy Controls and Parkinson Disease Patients

Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using ¹⁸F-FE-PE2I in Healthy Controls and Parkinson Disease Patients