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Randomized controlled trials are investigating the benefit of hepatic radioembolization added to systemic therapy in the first- and second-line treatment of patients with colorectal liver metastases (CRLM). Remarkably, administered activity may still be suboptimal, because a dose-response relationship has not been defined. The purpose of this study was to characterize the relationship between tumor-absorbed dose and response after (90)Y radioembolization treatment for CRLM.

the journal of nuclear medicine

Insights into the Dose–Response Relationship of Radioembolization with Resin <sup>90</sup>Y-Microspheres: A Prospective Cohort Study in Patients with Colorectal Cancer Liver Metastases

Insights into the Dose–Response Relationship of Radioembolization with Resin 90Y-Microspheres: A Prospective Cohort Study in Patients with Colorectal Cancer Liver Metastases

Insights into the Dose–Response Relationship of Radioembolization with Resin ⁹⁰Y-Microspheres: A Prospective Cohort Study in Patients with Colorectal Cancer Liver Metastases