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(225)Ac(3+) is a generator of α-particle-emitting radionuclides with 4 net α-particle decays that can be used therapeutically. Targeting (225)Ac(3+) by use of ligands conjugated to traditional bifunctional chelates limits the amount of (225)Ac(3+) that can be delivered. Ultrashort, single-walled carbon nanotubes (US-tubes), previously demonstrated as sequestering agents of trivalent lanthanide ions and small molecules, also successfully incorporate (225)Ac(3+).

Encapsulation of α-Particle–Emitting 225Ac3+ Ions Within Carbon Nanotubes

Encapsulation of α-Particle–Emitting ²²⁵Ac³⁺ Ions Within Carbon Nanotubes