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As the preparation phase of a multicenter clinical trial using (18)F-fluoro-2-deoxy-d-glucose ((18)F-FDG), (18)F-fluoromisonidazole ((18)F-FMISO), and 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) in non-small cell lung cancer (NSCLC) patients, we investigated whether 18 nuclear medicine centers would score tracer uptake intensity similarly and define hypoxic and proliferative volumes for 1 patient and we compared different segmentation methods.

the journal of nuclear medicine

Interobserver Agreement of Qualitative Analysis and Tumor Delineation of <sup>18</sup>F-Fluoromisonidazole and 3′-Deoxy-3′-<sup>18</sup>F-Fluorothymidine PET Images in Lung Cancer

Interobserver Agreement of Qualitative Analysis and Tumor Delineation of 18F-Fluoromisonidazole and 3′-Deoxy-3′-18F-Fluorothymidine PET Images in Lung Cancer

Interobserver Agreement of Qualitative Analysis and Tumor Delineation of ¹⁸F-Fluoromisonidazole and 3′-Deoxy-3′-¹⁸F-Fluorothymidine PET Images in Lung Cancer