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The cardioprotective effects of mesenchymal stem cells (MSCs) include reducing myocyte apoptosis, and this effect can be enhanced by preconditioning and encapsulation in a fibrin scaffold. This study aimed to test the hypothesis that apoptosis imaging can detect the cardioprotective effects of a conditioned MSC patch grafted in a rat model of acute myocardial infarction.

Noninvasive Imaging of Myocyte Apoptosis Following Application of a Stem Cell–Engineered Delivery Platform to Acutely Infarcted Myocardium