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In patients with inflammatory bowel disease (IBD) and in murine IBD models, mucosal disease activity is routinely assessed by endoscopy and histologic evaluation. This information is valuable for monitoring treatment response, with mucosal healing being a major treatment goal. The aim of this study was to evaluate the translational potential of noninvasive (18)F-FDG PET/CT for the assessment of mucosal damage in murine dextran sodium sulfate (DSS) colitis and human IBD.

Translational 18F-FDG PET/CT Imaging to Monitor Lesion Activity in Intestinal Inflammation

Translational ¹⁸F-FDG PET/CT Imaging to Monitor Lesion Activity in Intestinal Inflammation