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Although it has been believed that brown adipose tissue (BAT) depots disappear shortly after the perinatal period in humans, PET imaging using the glucose analog (18)F-FDG has shown unequivocally the existence of functional BAT in adult humans, suggesting that many humans retain some functional BAT past infancy. The objective of this study was to determine to what extent BAT thermogenesis is activated in adults during cold stress and to establish the relationship between BAT oxidative metabolism and (18)F-FDG tracer uptake.

15O PET Measurement of Blood Flow and Oxygen Consumption in Cold-Activated Human Brown Fat

¹⁵O PET Measurement of Blood Flow and Oxygen Consumption in Cold-Activated Human Brown Fat