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The endothelin subtype-A receptor (ET-A) is a promising therapeutic target in cardiovascular disease. We sought to determine the feasibility of an (18)F-labeled ligand, (18)F-(N-[[29-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,19-biphenyl]-2-yl]methyl]-N,4-fluorobenzamide) ((18)F-FBzBMS), for imaging ET-A in the healthy and injured rat heart.

Targeting of Endothelin Receptors in the Healthy and Infarcted Rat Heart Using the PET Tracer 18F-FBzBMS

Targeting of Endothelin Receptors in the Healthy and Infarcted Rat Heart Using the PET Tracer ¹⁸F-FBzBMS