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Changes in myocardial wall motion and thickening during myocardial perfusion SPECT are typically assessed separately from gated studies for the presence of stress-induced functional abnormalities. We sought to develop and validate a novel approach for automatic quantification of rest-stress myocardial motion and thickening changes (MTCs).

Direct Quantification of Left Ventricular Motion and Thickening Changes Using Rest–Stress Myocardial Perfusion SPECT